Home >> Study >> ForumTopic: QUERY IN MOCK TEST NO 917 AIIMS
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| docdesai Total Posts: 21 | Posted: Sun Oct 19, 2008 02:30 am Q 21. . MOST RADIOSENSITIVE 1) CA PANCREAS 2) CA OVARY 3) CA KIDNEY 4) CA CERVIX. . . ANSWER GIVEN IS CA PANCREAS WHICH IS THE MOST RADIORESISTANT ONE. . & AMONGST THE GIVEN OPTIONS THE BEST ANSWER IS CA OVARY . . . ISNT IT????? PLEASE HELP TO SOLVE THE QUERY. |
| superbdoc Total Posts: 273 | Posted: Sun Oct 19, 2008 06:00 am hello friend, I cant see your name.. 
But we have a thread running already here...https://www.netmedicos.com/?aiimsmdmsee2008nov/topic/3120/ Please contribute your queries abt mock test so that we can get a pool... Ya I too agree that Ca Pancreas is wrong and Ca Ovary is correct.... My ref is Devita textbook |
| docdesai Total Posts: 21 | Posted: Mon Oct 20, 2008 11:56 pm thanks for the confirmation & suggestion. . . please help me know how should i make my name seen by everyone? |
| jemzcal Total Posts: 127 | Posted: Tue Oct 21, 2008 01:14 am after logging in go to control panel (indicated by c panel near home icon) and change your current user name . hope you become visible soon. . |
| docdesai Total Posts: 21 | Posted: Tue Oct 21, 2008 04:23 am thanks jemzcal |
| juhidr Total Posts: 149 | Posted: Tue Oct 21, 2008 06:13 am Cell Radiosensitivity - is the relative susceptibility of cells to the injurious action of radiation - is directly proportional to the rate of cell division - is inversely proportional to the degree of cell differentiation - most radio-sensitive cells are those which: * have a high division rate * have a high metabolic rate * are of a non-specialized type * are well nourished - High Radiosensitivity: Lymphoid organs, bone marrow, blood, testes, ovaries, intestines - Fairly High Radiosensitivity: Skin and other organs with epithelial cell lining (cornea, oral cavity, esophagus, rectum, bladder, vagina, uterine cervix, ureters) - Moderate Radiosensitivity: Optic lens, stomach, growing cartilage, fine vasculature, growing bone - Fairly Low Radiosensitivity: Mature cartilage or bones, salivary glands, respiratory organs, kidneys, liver, pancreas, thyroid, adrenal and pituitary glands - Low Radiosensitivity: Muscle, brain, spinal cord Reference: Rubin, P. and Casarett. G. W.: Clinical Radiation Pathology (Philadelphia: W. B. Saunders. 1968). |
| juhidr Total Posts: 149 | Posted: Tue Oct 21, 2008 06:14 am So, ovaries and cervix cannot be answers. Pancreas and Kidney remain as options |
| kolsurgeon Total Posts: 13 | Posted: Tue Oct 21, 2008 07:45 am Hi, as a general surgeon I thought I might share my views with you. Ca Pancreas has been mentioned to be radioresistant in older textbooks, however, recently it has been found out that the addition of radiotherapy to surgery (Whipple's operation) achieves local control and prolongs survival in these patients thereby highlighting the radiosensitive nature of the tumor. Typically, fractionated EBRT is given but it might be toxic to adjacent tissues. What's more, a neoadjuvant chemoradiation protocol has been found out to be more suitable in these patients and improves survival (however, it does not control metastatic disease). Ovary is extremely radiosensitive but primary epithelial cancers of the ovary are not so therefore radiation therapy is not advised in the management of Ovarian CA. In Cervical CA, primary radiation therapy has a cure rate of 70% for Stage I, 60% for Stage II, 45% for Stage III and 18% for Stage IV. In addition, when postoperative radiation is administered as an adjuvant therapy, it is seen to decrease pelvic recurrences but not 5-yr survival rates so this is not as radiosensitive as compared to pancreatic CA. The essential point to remember that previous radiation therapies which were unfractionated had a high degree of toxicity in pancreatic CA but the tumor itself is responsive as highlighted by the increased survival with fractionated and neoadjuvant radiation therapies. (References from many surgical and gynecological texts) |
| superbdoc Total Posts: 273 | Posted: Tue Oct 21, 2008 02:23 pm WoW..!! our discussion has reasched new levels..
Whats the consensus answer now.?? |
| indent Total Posts: 54 | Posted: Tue Oct 21, 2008 09:58 pm So, the answer is kidney then. |
| indent Total Posts: 54 | Posted: Tue Oct 21, 2008 10:00 pm Sorry for the previous post. The answer for most radiosensitive = OVARIES The answer for most radioresistant = KIDNEY Anyone having a different opinion now can reply. |
| docdesai Total Posts: 21 | Posted: Wed Oct 22, 2008 12:06 am no differance is now to be considered. . done karo . . .stamped |
| kolsurgeon Total Posts: 13 | Posted: Wed Oct 22, 2008 12:42 am Most radiosensitive: CA Pancreas Most radioresistant: CA Kidney (if you would like to go with what I have tried to explain) |
| juhidr Total Posts: 149 | Posted: Wed Oct 22, 2008 02:40 am ok, i fully agree with you now, and that also means that the answer was correct (and now we have the explanation too) thanks Mr. Invisible (go to "CP" link on the top and change your nick name so that we can refer you by a name), you made our life easier.  |