Home >> Study >> ForumTopic: MONOCLONAL ANTIBODIES
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| Author: | Message |
| Varunrag Total Posts: 72 | Posted: Fri Sep 19, 2008 07:49 am infliximab inhibits TNF-α chimeric rheumatoid arthritis,Crohn's disease |
| Varunrag Total Posts: 72 | Posted: Fri Sep 19, 2008 07:51 am basiliximab inhibits IL-2 on activated T cells chimeric Acute rejection of kidney transplants |
| Varunrag Total Posts: 72 | Posted: Fri Sep 19, 2008 08:00 am abciximab Prevent coagulation in coronary angioplasty inhibits the receptor GpIIb/IIIa on platelets chimeric daclizumab Acute rejection of kidney transplants inhibits IL-2 on activated T cells-CD 25a humanized gemtuzumab relapsed acute myeloid leukaemia targets an antigen on leukemia cells -cd33 humanized alemtuzumab B cell leukemia targets an antigen CD52 on T- and B-lymphocytes humanized rituximab non-Hodgkin's lymphoma targets phosphoprotein CD20 on B lymphocytes chimeric palivizumab RSV infections in children inhibits an RSV protein humanized trastuzumab anti-cancer therapy for a specific kind of breast cancer Targets the HER2/neu (erbB2) receptor humanized etanercept rheumatoid arthritis TNF receptor Not an antibody |
| Varunrag Total Posts: 72 | Posted: Fri Sep 19, 2008 08:11 am DENOSUMAB monoclonal ab against RANKL receptor Used in treatment of osteoporosis ANAKINRA IL1 competitive blocker Used in RA (from latest Harrison) SUNITINIB VEGFR2 & PDGFR beta antibody Used in GIST and RCC SORAFINIB VEGFR2 & PDGFR beta/alpha Used in RCC ERLOTINIB EGFR Used in NON SMALL CELL CA LUNG & PANCREATIC CA GEFITINIB EGFR Used in NON SMALL CELL CA LUNG BORTEZOMIB PROTEOSOME Used in MULTIPLE MYELOMA PANITUMOMAB EGFR Used in CA COLON |
| Varunrag Total Posts: 72 | Posted: Fri Sep 19, 2008 08:16 am OMALIZUMAB ANTI IgE ASTHMA MUROMONAB ANTI CD3 OR OKT3 ALLOGRAFT REJECTION ADALIMUMAB ANTI TNF alpha RA EFALIZUMAB ANTI LFA1 (lymphocyte function associated antigen) ORGAN TRANSPLANTATION ,PSORIASIS BEVACIZUMAB ANTI VEGF COLORECTAL CA ,RCC |