Home >> Study >> ForumTopic: learn a Mab a day!!!!!
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| Author: | Message |
| jemzcal Total Posts: 127 | Posted: Fri Sep 19, 2008 06:37 am RITUXIMAB- ANTI CD20 used for NHL IBRITUMOMAB ANTI CD20 (Yittrium based) TOSITUMOMAB ANTI CD20 (Iodine based) **20 year old RITu |
| Varunrag Total Posts: 72 | Posted: Fri Sep 19, 2008 08:38 am sorry dude......didnt see this |
| jemzcal Total Posts: 127 | Posted: Sat Sep 20, 2008 01:16 am TRASTUZUMAB Anti Her2/neu used in Breast carcinoma **tras2/her2/breas2- they rhyme. don't they |
| jemzcal Total Posts: 127 | Posted: Sat Sep 20, 2008 08:37 pm PALIVIZUMAB Mab against RSV infection **PALI-----VI------ZU--------MAB PALI- remember as Pediatric Age Lung Infection VI- tells us that it is against a virus ZU- tells us it is a humanized mab MAB- general suffix |
| jemzcal Total Posts: 127 | Posted: Mon Sep 22, 2008 03:56 am OMALIZUMAB Mab against IgE **OMALEEEEE ===IgEEEEEEEEE |
| jemzcal Total Posts: 127 | Posted: Mon Sep 22, 2008 10:08 pm DACLIZUMAB and BASILIXIMAB both have same action.only difference is their mode of preparation as evident from their nomenclature. these are antibodies against IL-2 receptor(CD-25) LI in their names tells us that they have something to do with immunity. and u guessed it right , they act as immunosuppressants. **no codes this time folks. let me know if you come up with any. j |
| jemzcal Total Posts: 127 | Posted: Tue Sep 23, 2008 06:37 am DENOSUMAB targets RANKL (receptor activator for nuclear factor kappa ligand) used in osteoporosis **deno on rearranging done this sounds like bone So . . . . and the letter o(s) in any mab indicates that it has action on bone |
| jemzcal Total Posts: 127 | Posted: Wed Sep 24, 2008 06:49 am ABCIXIMAB Mab against gpIIb/IIIa used in individuals undergoing percutaneous coronary intervention to prevent thrombus formation/blood clotting. **abc= arrest blood clotting other drugs that act via the same mechanism EPTIFIBATIDE TIROFIBAN |
| jemzcal Total Posts: 127 | Posted: Thu Sep 25, 2008 06:20 am INFLIXIMAB Mab against TNF alpha can be used in psoriasis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, sarcoidosis and ulcerative colitis. **INF = TNF Other drugs with similar action ETANERCEPT ADALIMUMAB |
| jemzcal Total Posts: 127 | Posted: Fri Sep 26, 2008 06:10 am EFALIZUMAB Anti LFA-1(lymphocyte f'n associated antigen) uses- PSORIASIS **drug with related name and usage ALEFACEPT |
| jemzcal Total Posts: 127 | Posted: Sat Sep 27, 2008 12:44 pm Bevacizumab Mab against vascular endothelial growth factor (VEGF). It is used in the treatment of cancer, where it inhibits tumor growth by blocking the formation of new blood vessels (angiogenesis inhibitor) |
| jemzcal Total Posts: 127 | Posted: Mon Sep 29, 2008 07:24 am Panitumumab[/b] first fully human Mab specific to the EGF receptor . other drug with similar action Cetuximab both are used in colon carcinoma |
| jemzcal Total Posts: 127 | Posted: Tue Sep 30, 2008 10:09 am Gemtuzumab ozogamicin monoclonal antibody used to treat AML Anti CD33 |
| kari Total Posts: 1 | Posted: Wed Oct 01, 2008 09:55 pm |
| jemzcal Total Posts: 127 | Posted: Fri Oct 03, 2008 06:27 am Ranibizumab Mab against VEGF **used in ophthalmology for wet AMD |
| lazyguy666 Total Posts: 42 | Posted: Sat Oct 04, 2008 07:43 pm great info jemzcal |
| jemzcal Total Posts: 127 | Posted: Mon Oct 06, 2008 03:29 am Eculizumab Mab against C5 complement used in PNH |
| jemzcal Total Posts: 127 | Posted: Tue Oct 07, 2008 09:04 pm Ocrelizumab and Ofatumumab both are anti CD 20 ** so combining the earlier anti CD20 mabs that we discussed oFAT 20 year old RITu whoCRIEs |
| juhidr Total Posts: 149 | Posted: Tue Oct 07, 2008 09:37 pm Abagovomab is a mouse anti-idiotype monoclonal antibody whose variable epitope mirrors a tumour antigen (CA-125) highly expressed in the epithelial ovarian cancer. Abagovomab does not bind directly to CA-125, but it works as a "surrogate" antigen, enabling the immune system to identify and attack tumour cells displaying the CA 125 protein. Through this, it is hoped that the body's immune system may be able to combat any remaining individual tumour cells and thus prevent recurrence of the disease. Contents Abagovomab is currently under clinical development in patients with advanced ovarian cancer, as consolidation of the remission status obtained following surgery and standard platinum and taxane first line chemotherapy. In ovarian cancer Abagovomab is potentially capable of deferring or even preventing the occurrence of the relapse. MIMOSA trial (Monoclonal antibody Immunotherapy for Malignancies of the Ovary by Subcutaneous Abagovomab) - multicenter clinical trial in patients with ovarian cancer, in which after first line therapy with surgery and chemotherapy(paclitaxel und carboplatin), Abagovomab will be administered as maintenance therapy. |
| jemzcal Total Posts: 127 | Posted: Mon Oct 13, 2008 05:17 am MUROMONAB also called OKT 3 this is a mab against CD3 this is the first mab to be used it is used as immunosuppressive therapy for renal hepatic and heart transplant ** note that its nab and not mab |
| mady007 Total Posts: 8 | Posted: Mon Oct 13, 2008 06:45 pm veeeeeeeeeeeeerrrrrrrrrrrrrrrrrryyyyyyyyyyyy nice |
| juhidr Total Posts: 149 | Posted: Mon Oct 13, 2008 09:52 pm Capromab - Used to detect prostate cancer - Monoclonal antibody that binds to prostate cells - Combined with indium 111 and injected into the body - A gamma camera is used to find prostate cancer cells in the body - A type of immunoconjugate - Also called ProstaScint. |
| juhidr Total Posts: 149 | Posted: Mon Oct 13, 2008 09:55 pm Capromab = Ca---pro---MAB Ca---Pro = Cancer of Prostate MAB = Monoclonal Antibody |
| jemzcal Total Posts: 127 | Posted: Wed Oct 15, 2008 06:31 am NATALIZUMAB mab against cellular adhesion molecule integrin alpha4 uses CROHNS DISEASE MULTIPLE SCLEROSIS **courtesy varuchinu |
| juhidr Total Posts: 149 | Posted: Thu Oct 16, 2008 02:36 am Bapineuzumab - monoclonal antibody to the beta-amyloid (Aβ) plaques that are believed to underlie Alzheimer's disease - acts on the nervous system - potential therapeutic value for the treatment of Alzheimer's disease and possibly glaucoma |
| varuchinu Total Posts: 44 | Posted: Sat Oct 18, 2008 03:55 pm TNF alpha inhibitors --- [ rearrange -- TNF to TiFiN] Infliximab [ influx..] Eatanercept [ eat ] Adalimumab [ adali ... idli] find a similarity .... in all these ... it is all related to eating ... eat[eatanercept] ... idli[adalimumab]... influx [infliximab ] |
| jemzcal Total Posts: 127 | Posted: Sat Oct 18, 2008 05:06 pm now i will never forget how to eat/influx idli from a tiffin. thanks |
| jemzcal Total Posts: 127 | Posted: Mon Oct 20, 2008 05:50 am well friends i guess we have covered almost all important mabs that have been approved till date by FDA that are of relevance to us. hope that we all get in this time around. Otherwise the mabs that are in phase III and II will be out. It was a pleasure discussing with u all. hope you all had a pleasant journey onboard flight mab signing off. . j |
| juhidr Total Posts: 149 | Posted: Tue Oct 21, 2008 06:19 am Alemtuzumab - antibody against CD52 (present on both B cells and T cells) - used to treat some patients with B-cell chronic lymphocytic leukemia (B-CLL) |