Home >> Pharmacology >> ForumTopic: drugs c/i in g6pd deficiency
You need to be logged in to post messages.
| Author: | Message |
| garima27 Total Posts: 6 | Posted: Mon Dec 07, 2009 07:03 am In todays mcq of the day: drugs c/i in g6pd deficiency a)chloroquine b)quinine c)primaquine d)pyrimethamine as per key ans is (d) bt i checked it on net on(https://www.fpnotebook.com/Hemeonc/Pharm/MdctnsInG6pdDfcncy.htm)chloroquine is said to be safe. also aspirin & acetaminophen are NOW safe in contrast to what is mentioned in most books. please confirm |
| Admin Total Posts: 890 | Posted: Tue Dec 08, 2009 12:56 am Medications to Avoid in G6PD Deficiency 1. Anti-Malarials 1. Primaquine 2. Pamaquine 2. Sulfonamides 1. Sulfacetamide 2. Sulfanilamide 3. Sulfamethoxazole (e.g. Septra, Bactrim) 4. Sulfasalazine 3. Anti-bacterials 1. Nitrofurantoin 2. Nalidixic Acid 3. Dapsone 4. Mafenide Cream (Sulfamylon) 4. Analgesics 1. Phenacetin 2. Acetanilid 3. Phenazopyridine (Pyridium) 5. Miscellaneous 1. Quinine 2. Flutamide (Eulexin) 3. Methylene Blue 4. Rasburicase Medications safe in G6PD 1. General 1. Drugs previously thought contraindicated in G6PD 2. May not apply to Class I G6PD 2. Analgesics 1. Acetaminophen 2. Aspirin 3. Auralgan 3. Cardiovascular Agents 1. Procainamide 2. Quinidine 4. Neurologic Agents 1. Trihexyphenidyl 2. Levodopa 3. Phenytoin 5. Antibiotics 1. Chloramphenicol 2. Chloroquine 3. Isoniazid 4. Probenecid 5. Proguanil 6. Pyrimethamine 6. Miscellaneous 1. Vitamin C 2. Colchicine 3. Diphenhydramine So, Both the drugs are not contraindicated in G6PD deficiency. Only one needs to be cautious. |