A) Familial Mediterranean fever B) Familial amyloidotic polyneuropathy C) Dialysis associated amyloidosis D) Prion protein associated amyloidosis Answer (Select an option above to get the answer):
A) Patiens with IgD myeloma may present with no evident M-spike on serum electrophoresis B) A diagnosis of plasma cell leukemia can be made if circulating peripheral blood plasmablasts comprise 14% of peripheral blood white cells in a patient with white blood cell count of 11 X 100 /L and platelet count of 88 X 109 /L C) In smoldering myeloma plasma cells constitute 10 - 30% of total bone marrow cellularity D) In a patient with multiple myeloma, a monoclonal light chain may be detected in both serum and urine Answer (Select an option above to get the answer):
A) Fraction of cells in apoptotic pathways B) Fraction of cells in S phase C) p53 gene product D) bcr/abl gene Answer (Select an option above to get the answer):
(Single Best Answer) Question 87: Which one of the following serum levels would help in distinguishing an acute liver disease from chronic liver disease ?
A) Aminotransferase B) Alkaline phosphatase C) Bilirubin D) Albumin Answer (Select an option above to get the answer):
A) Hepatitis B virus infection B) Wilson's disease C) Hepatitis C virus infection D) Chronic alcoholism Answer (Select an option above to get the answer):
(Single Best Answer) Question 90: A 48 year old woman was admitted with a history of weakness for two months. On examination, cervical lymph nodes were found enlarged and spleen was palpable 2 cm below the costal margin. Her hemoglobin was 10.5 g/dl, platelet count 237 X 109 / L and total leukocyte count 40 X 109 /L, which included 80% mature lymphoid cells with coarse clumped chromatin. Bone marrow revealed a nodular lymphoid infiltrate. The peripheral blood lymphoid cells were positive for CD19, CD5, CD20, CD23 and were negative for CD79B and FMC-7. The histopathological examination of the lymph node in this patient will most likely exhibit effacement of lymph node architecture by ?
A) A pseudofollicular pattern with proliferation centers B) A monomorphic lymphoid proliferation with a nodular pattern C) A predominantly follicular pattern D) A diffuse proliferation of medium to large lymphoid cells with high mitotic rate Answer (Select an option above to get the answer):