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(Single Best Answer) Question 41: Recurrent facial / oropharyngeal / laryngeal edema in a patient who has low C4, normal C3 and normal factor B. The pathogenesis is most likely due to ?

A) Immune complex disease
B) C1 esterase inhibitors deficiency
C) Hereditary deficiency of C1
D) Classical pathway activation by IgM
Answer (Select an option above to get the answer):

(Single Best Answer) Question 42: The hypersensitivity reaction involved in the hyper acute rejection of renal transplant is ?

A) Type I
B) Type II
C) Type III
D) Type IV
Answer (Select an option above to get the answer):

(Single Best Answer) Question 43: Which of the following is known as the "guardian of the genome" ?

A) p53
B) Mdm2
C) pl4
D) ATM
Answer (Select an option above to get the answer):

(Single Best Answer) Question 44: Chemotherapeutic drugs can cause ?

A) Only necrosis
B) Only apoptosis
C) Both necrosis and apoptosis
D) Anoikis
Answer (Select an option above to get the answer):

(Single Best Answer) Question 45: Tectal breaking is seen in ?

A) Dandy-Walker malformation
B) Arnold-Chiari malformation
C) Aqueductal stenosis
D) Third ventricular tumor
Answer (Select an option above to get the answer):

(Single Best Answer) Question 46: The presence of small sized platelets on the peripheral smear is characterstic of ?

A) Idiopathic thrombocytopenic purpura
B) Bernard Soulier Syndrome
C) Disseminated intravascular coagulation
D) Wiskott Aldrich syndrome
Answer (Select an option above to get the answer):

(Single Best Answer) Question 47: The most likely inheritance pattern depicted in the following pedigree is :
                                    □ ┬ ●
                                        │
                                  ┌─┴┬─┬──┐
                                   ■     ○   □     ●
                       ┌───┼──┬──┬─┬─┐
                       ●         ●      □     □    □ ●
                    ┌┴┐      │   ┌┴┐
                    □   ●      ■   □    □

A) Autosomal dominant
B) X-linked recessive
C) X-linked dominant
D) Autosomal recessive
Answer (Select an option above to get the answer):

(Single Best Answer) Question 48: Which of the following chemical mediators of inflammation is an example of a C-X-C or alpha chemokine ?

A) Lipoxin LXA4
B) Interleukin IL-8
C) Interleukin IL-6
D) Monocyte Chemoattractant Protein MCP-1
Answer (Select an option above to get the answer):

(Single Best Answer) Question 49: Transition from G2 to M phase of the cell cyle is controlled by ?

A) Retinoblastoma gene product
B) p53 protein
C) Cyclin E
D) Cyclin B
Answer (Select an option above to get the answer):

(Single Best Answer) Question 50: Which of the following is not a cyclin dependent kinase (CDK) inhibitor ?

A) p21
B) p27
C) p53
D) p57
Answer (Select an option above to get the answer):