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Mcqs MBBS Exams India
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(Single Best Answer) Question 181: The amino acid which is associated with atherosclerosis is ?
A) Lysine
B) Homocysteine
C) Cysteine
D) Alanine
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(Single Best Answer) Question 182: CA - 125 is a marker antigen for the diagnosis of ?
A) Colon cancer
B) Breast cancer
C) Brain cancer
D) Ovarian cancer
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(Single Best Answer) Question 183: Amyloid deposits stain positively with all of the following except ?
A) Congo-red
B) Crystal violet
C) Methenamine silver
D) Thioflavin T
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(Single Best Answer) Question 184: Which one of the following brain tumors is highly vascular in nature ?
A) Glioblastoma
B) Meningiomas
C) C P angle epidermoid
D) Pituitory adenomas
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(Single Best Answer) Question 185: A 50-year-old male presented with signs and symptoms of restrictive heart disease. A right ventricular endo-myocardial biopsy revealed deposition of extra cellular eosinophilic hyaline material. On transmission electron microscopy, this material is most likely to reveal the presence of ?
A) Non branching filaments of indefinitive length
B) Cross banded fibres with 67 nm periodicity
C) Weber Palade bodies
D) Concentric whorls of lamellar structures
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(Single Best Answer) Question 186: An undifferentiated malignant tumour on immunohistochemical stain shows cytoplasmic positivity of most of the mtumour cell for cytokeratin. The most probable diagnosis of the tumour is ?
A) Sarcoma
B) Lymphoma
C) Carcinoma
D) Malignant Melanoma
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(Single Best Answer) Question 187: Sections from a solid-cystic unilateral ovarian tumour in 30 year old female show a tumour composed of diffuse sheets of small cells with doubtful nuclear grooving and scanty cytoplasm. No Call-Exner bodies are seen. The ideal immunohistochemistry panel would include ?
A) Vementin, epithelial membrane antigen, inhibin, CD99
B) Desmin, S- 100 protein, smooth muscle antigen, cytokeratin
C) Chromogranin, CD 45, CD 99, CD 20
D) CD 3, chromagranin, Cd 45, synaptophysin
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(Single Best Answer) Question 188: A 50-year-old lady presented with a 3 moth history of pain in the lower third of the right thigh. There was no local swelling; tenderness was present on deep pressure. Plain X-rays showed an ill-defined intra medullary lesion with blotchy calcification at the lower end of the right femoral diaphysis, possibly enchondroma or chondrosarcoma. Sections showed a cartilaginous tumour. Which of the following histological features (if seen) would be helpful to differentiate the two tumours ?
A) Focal necrosis and lobulation
B) Tumour permeationbetween bone trabeculae at periphery
C) Extensive myxoid change
D) High cellularity
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(Single Best Answer) Question 189: The differential diagnoses of lesion, histologically resembling giant cell tumour in the small bones of the hands or feet, includes all of the follwing except ?
A) Aneurysmal bone cyst
B) Fibrosarcoma
C) Osteosarcoma
D) Hyperparathyroidism
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(Single Best Answer) Question 190: Which of the following statements about carcinogenesis is false ?
A) Asbestos exposure increases the incidence of lung cancer
B) Papilloma viruses produce tumours in animals but not in humans
C) Exposure to aniline dyes predisposes to cancer of the urinary bladder
D) Hepatitis B virus has been implicated in hepatocellular carcinoma
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