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Mcqs MBBS Exams India
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(Single Best Answer) Question 121: A metastatic carcinoma in the brain of an adult, most often comes from a primary in the ?
A) Stomach
B) Ovary
C) Oral cavity
D) Lung
Answer (Select an option above to get the answer):
(Single Best Answer) Question 122: Features, which are evaluated for histological grading of breast carcinoma, include all of the following except ?
A) Tumor necrosis
B) Mitotic count
C) Tubule formation
D) Nuclear pleomorphism
Answer (Select an option above to get the answer):
(Single Best Answer) Question 123: Which of the following is not a common site for metastatic calcification ?
A) Gastric mucosa
B) Kidney
C) Parathyroid
D) Lung
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(Single Best Answer) Question 124: Internucleosomal cleavage of DNA is characteristic of ?
A) Reversible cell injury
B) Irreversible cell injury
C) Necrosis
D) Apoptosis
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(Single Best Answer) Question 125: On electron microscopy, amyloid characteristically exhibits ?
A) beta - pleated sheet
B) Hyaline globules
C) 7.5 - 10 nm fibrils
D) 20 - 25 nm fibrils
Answer (Select an option above to get the answer):
(Single Best Answer) Question 126: Which of the following is not compatible with a diagnosis of juvenile myelomonocytic leukemia ?
A) Peripheral blood monocytosis, more than 1 X 109/L
B) Increased hemoglobin F levels for age
C) Presence of bcr/abl fusion gene
D) GM-CSF hypersensitivity of myeloid progenitors in vitro
Answer (Select an option above to get the answer):
(Single Best Answer) Question 127: A 48 year old woman was admitted with a history of weakness for two months. On examination, cervical lymph nodes were found enlarged and spleen was palpable 2 cm below the costal margin. Her hemoglobin was 10.5 g/dl, platelet count 237 X 109/L and total leukocyte count 40 X 109/L, which included 80 % mature lymphoid cells with coarse clumped choromatin. Bone marrow revealed a nodular lymphoid infiltrate. The peripheral blood lymphoid cells were positive for CD19, CD5, CD20 and CD23 and were negative for CD79B and FMC-7. What is the most likely diagnosis ?
A) T-cell rich B-cell lymphoma with leukemic spill over in blood
B) Chronic lymphocytic leukemia
C) Mantle cell lymphoma
D) A definite diagnosis cannot be made in this patient without lymph node biopsy
Answer (Select an option above to get the answer):
(Single Best Answer) Question 128: All of the following are examples of a round cell tumor, except ?
A) Neuroblastoma
B) Ewing's sarcoma
C) Non Hodgkin's Lymphoma
D) Osteosarcoma
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(Single Best Answer) Question 129: Which of the following surface glycoproteins is most often expressed in human hematopoietic stem cell ?
A) CD22
B) CD40
C) CD15
D) CD34
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(Single Best Answer) Question 130: The tumor suppressor gene p53 induces cell cycle arrest at ?
A) G2 - M phase
B) S - G2 phase
C) G1 - S phase
D) G0 phase
Answer (Select an option above to get the answer):