Home >> Study >> Chemotherapy >> ForumTopic: Please ans my question: What is PPAP-A in Down's syndrome?
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| tutaibabu Total Posts: 11 | Posted: Tue May 20, 2008 03:53 am While reading one mcq, I came accross the term PPAP-A in Down's syndrome. Later I found out that it is pregnancy associated plasma protein A and is used for screening of Down's syndrome. Can any of you please give more details about this? |
| gourab Total Posts: 12 | Posted: Tue May 20, 2008 04:29 am It is PAPPA an metallopeptidase.it cleaves insulin-like growth factor binding proteins.. its low level is associated with high risk of IUGR,Trisomy21,preeclampsia, etc.. its high level is associated with acute coronary syndrome, atherosclerosis.... |
| sanju5 Total Posts: 138 | Posted: Tue May 20, 2008 05:39 am thanks buddy |